Constipation      Piles

Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism also damage vascular structures in the anal canal.

     Less Sweating

Piles - Hemorrhoid

When you  are constipated, you are more likely to push hard to try to go. That can make the veins around your rectum and anus swell. These swollen veins are called hemorrhoids, or piles. They are like varicose veins around your anus.